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Research We Fund: Extramural Discovery Science

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Molecular Biology and Biochemistry (PF-MBB)

Areas Reviewed

  • Gene regulation, transcription, epigenetics, translation, RNA replication, DNA repair, and recombination

  • Structural biology (DNA, RNA, proteins, and/or other macromolecules)

  • Functional and structural changes in RNA in carcinogenesis including RNA processing, miRNAs, lncRNAs, and translation

  • Cell signaling

  • Cellular metabolism

  • Protein degradation

  • Tumor-related changes in cellular lipid, carbohydrate, and protein chemistry associated with altered enzyme function

  • Cancer-related changes in endocrinology, hormone receptors, and hormone function

  • Biochemistry of cell growth factors, membrane receptors, and the signaling pathways by which hormones control cell growth and cell differentiation

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