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After Ovarian Cancer Treatment

For some people with ovarian cancer, treatment may remove or destroy the cancer. Completing treatment can be both stressful and exciting. You will be relieved to finish treatment, yet it is hard not to worry about cancer coming back (recurrence). This is very common if you've had cancer.

For others, ovarian cancer never goes away completely. Some women may be treated with chemotherapy on and off for years. Learning to live with cancer that does not go away can be difficult, but many women find ways to manage their health and maintain a good quality of life.

Follow up care after ovarian cancer

Talk with your doctor about developing a survivorship care plan for you. This plan can guide your next steps after treatment, including follow-up appointments and ways to stay healthy.

What¡¯s usually in a survivorship care plan

A survivorship care plan might include:

  • A suggested schedule for follow-up exams and tests
  • A timeline for other tests, such as screening for other cancers, or monitoring for long-term health effects from your cancer or its treatment
  • A list of possible late or long-term side effects, including what to watch for and when you should contact your doctor
  • Diet and physical activity suggestions
  • Reminders to keep seeing your primary care provider (PCP) for regular health care and cancer screening tests.

Typical follow-up schedules after ovarian cancer

Even if you have completed treatment, you will likely have follow-up visits with your doctor for many years. It is very important to go to all of these appointments. These visits often include exams, lab tests, x-rays, or other scans to look for signs of cancer or treatment side effects.

Some cancer treatment side effects may last a long time or might not even show up until years after you have finished treatment. Your doctor visits are a good time to ask questions and talk about any changes or problems you notice or concerns you have.

Imaging tests

Depending on the stage of your cancer, and other factors such as any symptoms or other concerning signs, your doctor may recommend CT scans, MRIs, or PET scans.

Blood tests for tumor markers

Follow-up for ovarian cancer usually includes blood tests for tumor markers or hormones to check for cancer recurrence:

  • For epithelial ovarian cancer, CA-125 is the tumor marker used most often to check for recurrence. However, it is not clear if checking for CA-125 levels and treating you before you have symptoms will help you live longer. Treatment based only on CA-125 levels and not symptoms can increase side effects, so it is important to discuss the pros and cons of CA-125 monitoring and quality of life with your doctor. Tests for other tumor markers, such as CA 19-9, CEA, and HE-4, can be used for women whose CA-125 levels never went up.
  • For germ cell tumors, blood is tested for alpha-fetoprotein (AFP) and/or human chorionic gonadotropin (HCG) levels.
  • For stromal cancers, checking levels of hormones like estrogen, testosterone, and inhibin is sometimes helpful.

Questions to ask your care team

  • Are there any limits on what I can do?
  • What other symptoms should I watch for?
  • What kind of exercise should I do now?
  • What type of follow-up will I need after treatment?
  • How often will I need to have follow-up exams and imaging tests?
  • Will I need any blood tests?
  • How will we know if the cancer has come back? What should I watch for?
  • What will my options be if the cancer comes back?

Staying prepared and organized

Even if you¡¯ve completed treatment, it¡¯s still important to be organized and stay on top of your health. Keeping your records and health insurance coverage in order makes it easier to manage follow-up care, future checkups, and any new concerns that may come up.

Keep your health insurance

It¡¯s very important to keep health insurance as an ovarian cancer survivor. It can help cover the cost of follow-up visits, tests, and any care you may need in the future. No one wants to think about cancer coming back, but it¡¯s best to be prepared.

Save your medical records

At some point, you may see a new doctor who doesn¡¯t know your cancer history. Keep copies of your medical records so you can easily share the details of your diagnosis and treatment when needed.

Can I lower my risk of the ovarian cancer progressing or coming back?

If you have (or have had) ovarian cancer, you probably want to know if there are things you can do that might lower your risk of the cancer growing or coming back. While there are some things you can do that might be helpful, more research is needed to know for sure.

Get regular physical activity

Some studies have shown that women who are more physically active after being diagnosed with ovarian cancer might live longer. More research is being done in this area.

Adopt other healthy behaviors

Adopting healthy behaviors such as not smoking, eating well, and staying at a healthy weight might help lower the risk of recurrence, but no one knows for sure. However, we do know that these types of changes can have other health benefits.

About dietary supplements

So far, no dietary supplements (including vitamins, minerals, and herbal products) have been shown to clearly help lower the risk of ovarian cancer progressing or coming back. This doesn¡¯t mean that no supplements will help, but it¡¯s important to know that none have been proven to do so.

Dietary supplements are not regulated like medicines in the United States ¨C they do not have to be proven effective (or even safe) before being sold, although there are limits on what they¡¯re allowed to claim they can do. If you¡¯re thinking about taking any type of nutritional supplement, talk to your health care team. They can help you decide which ones you can use safely while avoiding those that might be harmful.

If the cancer comes back

If the cancer does recur at some point, your treatment options will depend on where the cancer is located, what treatments you¡¯ve had before, and your health.

See Understanding Recurrence to learn more.

Do ovarian cancer survivors have a higher risk of other cancers?

Some people may develop a new, unrelated cancer after treatment. This is called a second cancer. Ovarian cancer survivors can get any type of second cancer, but they have an increased risk of:

Studies have shown that the risk of developing solid tumors is higher during all follow-up periods after ovarian cancer.

Can I lower my risk of getting a second cancer?

There are steps you can take to stay healthy and lower your risk of getting another cancer. Ovarian cancer survivors are encouraged to:

These habits may also lower the risk of other health problems.

Getting emotional support

Some amount of feeling depressed, anxious, or worried is normal when cancer is a part of your life. Some people are affected more than others. But everyone can benefit from help and support from other people, whether friends and family, religious groups, support groups, professional counselors, or others. Learn more in Life After Cancer.

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Developed by the ÁñÁ«ÊÓÆµ medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

Cannistra SA, Gershenson DM, Recht A. Ch 76 - Ovarian cancer, fallopian tube carcinoma, and peritoneal carcinoma. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 10th ed. Philadelphia, PA: Lippincott

Morgan M, Boyd J, Drapkin R, Seiden MV. Ch 89 ¨C Cancers Arising in the Ovary. In: Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, Kastan MB, McKenna WG, eds. Clinical Oncology. 5th ed. Philadelphia, PA: Elsevier; 2014: 1592.

Rock CL, Thomson C, Gansler T, et al. ÁñÁ«ÊÓÆµ guideline for diet and physical activity for cancer prevention. CA: A Cancer Journal for Clinicians. 2020;70(4). doi:10.3322/caac.21591. Accessed at https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21591 on June 25, 2025.

Rock CL, Thomson CA, Sullivan KR, et al. ÁñÁ«ÊÓÆµ nutrition and physical activity guideline for cancer survivors. CA Cancer J Clin. 2022. https://doi.org/10.3322/caac.21719.

Last Revised: August 8, 2025

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